BR-EASE - Brazilian Eye and Skin Estimator

Forensic DNA phenotyping aims to predict appearance traits of an individual based on a DNA sample. Eyes and Skin colors are highly heritable genetic traits and are the most obvious and distinguishable externally visible characteristics to be used for human identification. Genotype-phenotype association studies have focused in detecting single nucleotide polymorphisms (SNPs) within genes directly or indirectly involved in pigments synthesis. Here, we introduce you to an easy system for eyes and skin phenotype prediction through DNA.

Instructions:
- Select the corresponding genotypes in the selection box and click below to predict the phenotype.
- Eyes phenotypes are divided into three classes: Blue, Intermediate and Brown.
- Skin phenotypes are divided into three classes: Light, Intermediate and Dark.
- Information about genes and SNPs are available on the corresponding links.

@ If you have any questions, please contact us. Email: carlosibaldo@gmail.com

BR-EASE: Eye Color Estimator

Ten SNPs were selected in the following human pigmentation associated genes: ASIP (rs6119471), DDB1 (rs11230664), HERC2 (rs6497271, rs1129038, rs12913832), MFSD12 (rs10424065, rs6510760), OCA2 (rs1800407), SLC24A5 (rs1426654) and SLC24A4 (rs2402130).

SNP Panel for Eye Color Prediction
ASIP
DDB1
HERC2
HERC2
HERC2
MFSD12
MFSD12
OCA2
SLC24A5
SLC24A4


Version (Release): 1.0 (05/03/2019)
Classifier: Random Forest

BR-EASE: Skyn Color Estimator

Twenty Five SNPs were selected in the following human pigmentation associated genes: ASIP (rs2424984, rs6119471), DDB1 (rs11230664), HERC2 (rs1129038, rs11636232, rs16950987, rs2238289, rs4932620, rs6497271), MC1R (rs1805006, rs1805009, rs3212345, rs885479), MFSD12 (rs10424065, rs6510760), NPLOC4 (rs9894429), OCA2 (rs1037208, rs1375164, rs3794606, rs4778232), SLC24A5 (rs1426654), SLC45A2 (rs16891982, rs183671), TMEM138 (rs7948623) and TYR (rs1042602).

SNP Panel for Skin Color Prediction
ASIP
ASIP
DDB1
HERC2
HERC2
HERC2
HERC2
HERC2
HERC2
MC1R
MC1R
MC1R
MC1R
MFSD12
MFSD12
NPLOC4
OCA2
OCA2
OCA2
OCA2
SLC24A5
SLC45A2
SLC45A2
TMEM138
TYR



Version (Release): 1.0 (05/03/2019)
Classifier: Support Vector Machine
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